Mr. Ruben Beltran Palafox, Director of the Economic Cooperation Department of the Ministry of Foreign Affairs of Mexico, introduced the Mexican Entrepreneurship Institution established in 2004.Supporting entrepreneurship has become a national priority since the early 1990s to reduce informal economy and to increase the number of right holders enrolled in the national social security system.Promoting entrepreneurship and supporting MSMEs and startups are complimentary intertwined strategies.The institution works closely with but not under the leadership of the Department of Economic Cooperation. It aims to pool together a variety of entrepreneurial ideas, projects, factors, technical tools and other elements for entrepreneurs. The institution has played a significant role in building national entrepreneurship fund, network and social security system and regulating entrepreneurs in fulfilling their legal obligations as employers. All these show that Mexican government’s constant explorations in protecting entrepreneurs and their employees’ interests.